Batch-Normalized Toxin Yield
VC-MET-211 — grams of finished compound recovered per kilogram of input biomass — the mass-efficiency view of yield.
Definition
Batch-Normalized Toxin Yield expresses finished-compound mass recovered per kilogram of input biomass (g·kg⁻¹), normalizing raw yield against the feedstock consumed so batches of different size are directly comparable.
Why it matters
Raw yield rises and falls with batch size; normalizing to input biomass isolates true process efficiency. It is the figure the Directorate uses to compare cultivar lines and to detect a degrading reactor independent of throughput.
Formula
Y_norm = m_compound / m_biomass_in [g · kg⁻¹] m_compound = net finished mass after purification m_biomass_in = green weight charged to the reactor Cross-check: Y_norm ≈ C_alk(VC-MET-200) · η_ext(VC-MET-217) Deviation > 8 % between measured and predicted flags an unaccounted process loss.
Inputs
| Input | Detail | Source |
|---|---|---|
| Finished mass | Net post-purification weight | Lab |
| Input biomass | Green charge weight | CHLORA |
| Predicted yield | C_alk × extraction efficiency | CHLORA |
Units & Scale
g·kg⁻¹ biomass to one decimal place, reported per batch with a rolling 10-batch mean. Aggregation is by simple mean over batches of the same cultivar line only.
Sampling & Source
- Computed per batch at reactor closeout from lab and charge data.
- Reconciled against predicted yield from concentration × purity.
- 10-batch rolling mean trended for reactor health.
Thresholds
OK
WARN
CRIT
Recent Trend
Zone roll-up, last 14 sampling periods (current 11.2):
Interpretation Guidance
| Band | Reading | Likely Driver | Action |
|---|---|---|---|
| 12–13 | Peak efficiency | Optimal reactor & feedstock | Log set-points as reference. |
| 9.5–11.9 | Nominal | Normal process variation | None. |
| 7.5–9.4 | Soft loss | Transfer or extraction loss | Inspect reactor; check VC-MET-219. |
| < 7.5 | WARN / CRIT | Reactor fault | Hold; teardown & reconciliation. |
Related Metrics
Toxin Yield Rate
Un-normalized throughput.
VC-MET-200Alkaloid Concentration
Feedstock potency term.
VC-MET-217Extraction Purity
Efficiency term.
VC-MET-219Reactor Conversion Efficiency
Process driver.
Related SOPs
- Reactor closeout & reconciliation — SOP Library.